学术团队

Academic team

瑕瑜 Yu XIA

2021-06-23
职位 教授,博士生导师 Tel Tel: 86-10-62799232
MAIL Email: xiayu@mail.tsinghua.edu.cn

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瑕瑜Yu XIA

教授,博士生导师

国家杰出青年科学基金获得者

Tel: 86-10-62799232

Email: xiayu@mail.tsinghua.edu.cn

1999年毕业于兰州大学化学系,获学士学位,2002年获中科院上海药物研究所硕士,2006年获得Purdue University(普渡大学)化学系博士学位。2007-2016于普渡大学化学系先后任博士后、助理研究员、助理教授及副教授,2016年秋起任清华化学系教授。研究方向包括发展自由基反应质谱系统及其在脂质组学和蛋白组学的应用方法研究。在本领域重要期刊包括Nat Commun, PNAS,JACS, Angew Chem, Anal Chem等发表论文90余篇。2013年获美国质谱学会的研究奖,2015-2017年担任美国质谱协会理事会秘书, 2017年获得国家优秀青年科学基金资助,2022年获国家杰出青年科学基金资助。现担任Journal of the American Society for Mass Spectrometry(2019-2024)和International Journal of Mass Spectrometry期刊编委(2020-2023)。


Dr. Yu Xia earned her B.S. (1999) in Chemistry from Lanzhou University, China, M.S. (2002) from Shanghai Institute of Material Medical, CASs, China, and Ph.D. (2006) under the supervision of Professor Scott A. McLuckey from Purdue University, USA. After postdoctoral training with Professor Graham R. Cooks at Purdue, Dr. Xia took positions as Assistant and Associate Professor at the Department of Chemistry, Purdue University (2009-2016). She joined the Department of Chemistry, Tsinghua University as a Professor from the fall of 2016.Her research directions include the development of radical reaction mass spectrometry systems and methods for lipidomics and proteomics applications. Her work has resulted in over 90 peer-reviewed publications and book chapters. Dr. Xia received ASMS Research Award (2013) and served as the Secretary of ASMS (2015-2017). She received the support from the National Natural Science Foundation for Excellent Young Scholar (2017). She currently serves on the editorial board of the Journal of the American Society for Mass Spectrometry(2019-2024)and International Journal of Mass Spectrometry (2020-2023).


代表性论文:

1.Adhikari, S.; Crehuet, R.; Anglada, J. M.*; Francisco, J. S.*;Xia, Y.*; Two-step Reaction Mechanism Reveals New Antioxidant Capability of Cysteine Disulfides Against Hydroxyl Radical Attack,Proc. Natl. Acad. Sci. USA, 2020,117, 18216-18223

2.Zhang, W.; Zhang, D.; Chen, Q.; Wu, J.; Ouyang, Z.*;Xia, Y.*; Online Photochemical Derivatization Enables Comprehensive Mass Spectrometric Analysis of Unsaturated Phospholipid Isomers,Nat. Commun.,2019, 10, 79

3.Zhao, X.; Zhang, W.; Zhang, D.; Liu, X.; Cao, W.; Chen, Q; Ouyang, Z.;Xia, Y.*; A Lipidomic Workflow Capable of Resolving sn- and C=C Location Isomers of Phosphatidylcholines,Chem. Sci.,2019, 10, 10740-10748

4.Ma, X.#; Chong, L.#; Tian, R.; Shi, R.; Hu, T. Y.; Ouyang, Z.*;Xia, Y.*; Identification and Quantitation of Lipid C=C Location Isomers: A Shotgun Lipidomics Approach Enabled by Photochemical Reaction,Proc. Natl. Acad. Sci. USA,2016, 113, 2573-2578

5.Ma X.;Xia, Y.*; “Pinpointing Double Bonds in Lipids by Paternò–Büchi Reactions and Mass Spectrometry”,Angew. Chem., Int. Ed,2014, 53, 2592-2596.

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