2004年毕业于清华大学化学系，获学士学位。2009年获清华大学化学系博士学位（导师：童爱军教授）。2009-2012于美国伊利诺伊大学香槟分校从事博士后研究（合作导师：Yi Lu教授），2012年起任清华大学化学系副教授。研究方向为基于核酸硫化学开发分析化学与化学生物学研究工具，包括：（1）基于硫化学的核酸合成后修饰方法；（2）化学修饰脱氧核酶用于刺激响应的生物传感和基因调控；（3）化学修饰向导RNA用于刺激响应的CRISPR/Cas基因编辑。现担任Sensors期刊编委会成员。

Dr. Yu Xiang got his B.S. in Chemistry (2004) from Tsinghua University, China, and Ph.D. in Chemistry (2009) under Prof. Aijun Tong in Tsinghua University. After the postdoctoral research (2009-2012) with Prof. Yi Lu at University of Illinois at Urbana-Champaign, Dr. Xiang has worked as an associate professor in Department of Chemistry at Tsinghua University since 2012. He is currently working on the sulfur chemistry for modified nucleic acids as tools in chemical biology, including (1) Sulfur chemistry for post-synthetic nucleic acid modification; (2) Chemically modified DNAzyme for stimuli-responsive biosensing and gene regulation; (3) Chemically modified guide RNA for stimuli-responsive gene editing mediated by CRISPR/Cas. He serves on the editorial board of the journal Sensors.

代表性论文：

1.Wang, J. Y.; Shang, J. C.; Qin, Z. C.; Tong, A. J.;Xiang, Y.*, Selective and Sensitive Fluorescence "Turn-On" Detection of 4-Thiouridine in Nucleic Acids via Oxidative Amination.Chemical Communications2019, 55, 13096-13099.

2.Xiao, L.#; Gu, C. M.#;Xiang, Y.*, Orthogonal Activation of RNA-Cleaving DNAzymes in Live Cells by Reactive Oxygen Species.Angewandte Chemie-International Edition2019, 58, 14167-14172.

3.Feng, M. L.; Gu, C. M.; Sun, Y. P.; Zhang, S. Y.; Tong, A. J.;Xiang, Y.*, Enhancing Catalytic Activity of Uranyl-Dependent DNAzyme by Flexible Linker Insertion for More Sensitive Detection of Uranyl Ion.Analytical Chemistry2019, 91, 6608-6615.

4.Xiao, L.; Zhou, Z. J.; Feng, M. L.; Tong, A. J.;Xiang, Y.*, Cationic Peptide Conjugation Enhances the Activity of Peroxidase-Mimicking DNAzymes.Bioconjugate Chemistry2016, 27, 621-627.

5.Wang, X. Y. #; Feng, M. L. #; Xiao, L.; Tong, A. J.;Xiang, Y.*, Postsynthetic Modification of DNA Phosphodiester Backbone for Photocaged DNAzyme.ACS Chemical Biology2016, 11, 444-451.